What is the initial treatment for a Holstein cow with a cystic structure on the ovary and anestrus since calving?

The initial treatment for a Holstein cow with a cystic structure on the ovary and anestrus since calving often involves administering Gonadotropin-Releasing Hormone (GnRH) followed by prostaglandin. This approach is effective because the GnRH stimulates the release of luteinizing hormone (LH), which can help induce ovulation of the cystic structure. Following this, prostaglandin is used to luteolyze any existing corpus luteum, which further helps to facilitate a normal estrous cycle.

In cases of ovarian cysts, the combination of these two hormones addresses both the potential underlying hormonal imbalance and the physical presence of the cyst. This treatment plan can restore normal reproductive function more effectively than other options, making it a standard initial approach in such scenarios.

Other treatments, such as administering follicle-stimulating hormone or melengestrol acetate, may not be the first line in these specific situations as they may not adequately address both the cystic structure and the anestrus condition simultaneously. Prostaglandin alone may lack the necessary stimulus to prompt ovulation, which is often needed in cases where cysts are present. Thus, the selection of GnRH followed by prostaglandin is a comprehensive